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Desmethyl-QCA276 [2126819-55-2]

Desmethyl-QCA276 [2126819-55-2]

T18601
TargetMol Chemicals
CAS Number2126819-55-2
Product group Chemicals
Molecular Weight387.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Desmethyl-QCA276 [2126819-55-2]
  • Delivery Days Customer
    999
  • CAS Number
    2126819-55-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Desmethyl-QCA276
  • Molecular Formula
    C21H17N5OS
  • Molecular Weight
    387.46
  • Scientific Description
    Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
  • Shelf life instruction
    3 years
  • SMILES
    C(#CC=1SC2=C(C1CC=3C=CC=CC3)COCC4=NN=C(N42)C)C=5C=NNC5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200