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ProductsBack/Desmorpholinyl Quizartinib-PEG2-COOH [2292116-14-2]

Desmorpholinyl Quizartinib-PEG2-COOH [2292116-14-2]

HY-131230
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Desmorpholinyl Quizartinib-PEG2-COOH [2292116-14-2]
  • Delivery Days Customer
    5
  • CAS Number
    2292116-14-2
  • Certification
    Research Use Only
  • Estimated Purity
    96.32
  • Molecular Formula
    C30H33N5O7S
  • Molecular Weight
    607.68
  • Scientific Description
    Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM[1].
  • SMILES
    O=C(O)CCOCCOCCOC1=CC=C2N3C(SC2=C1)=NC(C4=CC=C(NC(NC5=NOC(C(C)(C)C)=C5)=O)C=C4)=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41115800

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