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ProductsBack/Destruxin B [2503-26-6]

Destruxin B [2503-26-6]

Research Use Only
D183745
LKT Laboratories
Estimated Purity≥96%
Product group Chemicals
€ 161,00
100 ug
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Destruxin B [2503-26-6]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥96%
  • Scientific Description
    Cyclic depsipeptide is a secondary metabolite isolated from the fungus Metarhizium anisopliae.; MLS002702090; AC1L8LE6; MEGxm0_000393
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Yeh CT, Rao YK, Ye M, et al. Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging. Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41. PMID: 22465936. Odier F, Vey A, Bureau JP. In vitro effect of fungal cyclodepsipeptides on leukemic cells: study of destruxins A, B, and E. Biol Cell. 1992;74(3):267-271. PMID: 1628110. Dornetshuber-Fleiss R, Heffeter P, Mohr T, et al. Destruxins: fungal-derived cyclohexadepsipeptides with multifaceted anticancer and antiangiogenic activities. Biochem Pharmacol. 2013 Aug 1;86(3):361-377. PMID: 23747344. Muroi M, Shiragami N, Takatsuki A. Destruxin B, a specific and readily reversible inhibitor of vacuolar-type H(+)-translocating ATPase. Biochem Biophys Res Commun. 1994 Dec 15;205(2):1358-1365. PMID: 7802670. Chao PZ, Chin YP, Hsu IU, et al. Apoptotic toxicity of destruxin B in human non-Hodgkin lymphoma cells. Toxicol In Vitro. 2013 Sep;27(6):1870-1876. PMID: 23751424.