Desvenlafaxine [93413-62-8]

MedChem Express

Desvenlafaxine

9

93413-62-8

Research Use Only

98.0

C16H25NO2

263.38

Desvenlafaxine, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine shows weak binding affinity (62% inhibition at 100 microM) at the human dopamine (DA) transporter[1][2].

OC1=CC=C(C(C2(O)CCCCC2)CN(C)C)C=C1

-20°C,2°C to 8°C

12352200