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DGUOK Polyclonal Antibody

Research Use Only
RD84132A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDGUOK
Price on request
Packing Size
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    DGUOK Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1716
  • Target name
    DGUOK
  • Target description
    deoxyguanosine kinase
  • Target synonyms
    deoxyadenosine kinase, mitochondrial; deoxyguanosine kinase, mitochondrial; dGK; MTDPS3; NCPH; NCPH1; PEOB4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203