DGUOK Polyclonal Antibody
RD84132A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDGUOK
Overview
- SupplierReddot Biotech
- Product NameDGUOK Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1716
- Target nameDGUOK
- Target descriptiondeoxyguanosine kinase
- Target synonymsdeoxyadenosine kinase, mitochondrial; deoxyguanosine kinase, mitochondrial; dGK; MTDPS3; NCPH; NCPH1; PEOB4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionIn mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203