DHFR-IN-2

TargetMol Chemicals

DHFR-IN-2

65

331942-46-2

Chemical

DHFR-IN-2

C14H13NO2

227.26

DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR with an IC 50 of 7 uM. The enzyme dihydrofolate reductase from M.tuberculosis (MtDHFR) has a high unexploited potential to be a target for new drugs against tuberculosis (TB), due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].

3 years

C(NC1=CC=CC=C1)C2=CC(C(O)=O)=CC=C2

-20°

12352200