DHFR-IN-5

TargetMol Chemicals

DHFR-IN-5

65

1142407-81-5

Chemical

DHFR-IN-5

C18H24N4O4

360.41

DHFR-IN-5 is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a K i value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 shows anti-malaria activity .

3 years

O(CCCOC1=C(CCC(O)=O)C=CC=C1)C=2C(CC)=NC(N)=NC2N

-20°

12352200