DHH Polyclonal Antibody
RD266021A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDHH
Overview
- SupplierReddot Biotech
- Product NameDHH Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID50846
- Target nameDHH
- Target descriptiondesert hedgehog signaling molecule
- Target synonymsdesert hedgehog protein; GDMN; GDXYM; HHG-3; SRXY7
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203