DIABLO Polyclonal Antibody
RD82690A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDIABLO
Overview
- SupplierReddot Biotech
- Product NameDIABLO Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID56616
- Target nameDIABLO
- Target descriptiondiablo IAP-binding mitochondrial protein
- Target synonymsDFNA64; diablo homolog, mitochondrial; diablo-like protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; SMAC
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203