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Diallyl Trisulfide [2050-87-5]

Research Use Only
D3202
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 782,00
1 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Diallyl Trisulfide [2050-87-5]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Soluble in acetone. Slightly soluble in ethanol (3 mg/mL), DMSO (5 mg/mL), 2-propanol, and DMF (10 mg/mL).
  • Scientific Description
    Organosulfur found in garlic.; Allyl trisulfide, DATS, Allitridin
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Suda S, Watanabe K, Tanaka Y, et al. Identification of molecular target of diallyl trisulfide in leukemic cells. Biosci Biotechnol Biochem. 2014;78(8):1415-7. PMID: 25130746. Sumedha N, Miltonprabu S. Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats. Hum Exp Toxicol. 2014 Jul 25. [Epub ahead of print]. PMID: 25062976. Hung FM, Shang HS, Tang NY, et al. Effects of diallyl trisulfide on induction of apoptotic death in murine leukemia WEHI-3 cells in vitro and alterations of the immune responses in normal and leukemic mice in vivo. Environ Toxicol. 2014 May 28. [Epub ahead of print]. PMID: 24890016. Zhu X, Zhang F, Zhou L, et al. Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats. Naunyn Schmiedebergs Arch Pharmacol. 2014 May;387(5):445-55. PMID: 24557053. Hahm ER, Singh SV. Diallyl trisulfide inhibits estrogen receptor-alfa activity in human breast cancer cells. Breast Cancer Res Treat. 2014 Feb;144(1):47-57. PMID: 24487688. Shin DY, Cha HJ, Kim GY, et al. Inhibiting invasion into human bladder carcinoma 5637 cells with diallyl trisulfide by inhibiting matrix metalloproteinase activities and tightening tight junctions. Int J Mol Sci. 2013 Oct 1;14(10):19911-22. PMID: 24084732. Wallace GC 4th, Haar CP, Vandergrift WA 3rd, et al. Multi-targeted DATS prevents tumor progression and promotes apoptosis in ectopic glioblastoma xenografts in SCID mice via HDAC inhibition. J Neurooncol. 2013 Aug;114(1):43-50. PMID: 23754639. Lee HJ, Lee HG, Choi KS, et al. Diallyl trisulfide suppresses dextran sodium sulfate-induced mouse colitis: NF-kappaB and STAT3 as potential targets. Biochem Biophys Res Commun. 2013 Jul 26;437(2):267-73. PMID: 23811270. Li Y, Zhang J, Zhang L, et al. Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signaling. Carcinogenesis. 2013 Jul;34(7):1601-10. PMID: 23430952. Huang YT, Yao CH, Way CL, et al. Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats. J Appl Physiol (1985). 2013 Feb;114(3):402-10. PMID: 23139364.