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Dicentrine (hydrochloride)

Research Use Only
HY-N6969A
MedChem Express
Molecular Weight375.85
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Dicentrine (hydrochloride)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C20H22ClNO4
  • Molecular Weight
    375.85
  • Scientific Description
    Dicentrine hydrochloride is a drug with anti-inflammatory and anti-cancer activity. Dicentrine hydrochloride exerts its effects by enhancing TNF-alpha-induced apoptosis in A549 lung adenocarcinoma cells. Dicentrine hydrochloride increases caspase-8, -9, -3 and poly(ADP-ribose) polymerase (PARP) activities. Dicentrine hydrochloride inhibits TNF-alpha-induced invasion and migration of A549 cells. Dicentrine hydrochloride significantly inhibited the TNF-alpha-activated TAK1, p38, JNK and Akt signaling pathways, and reduced the transcriptional activities of NF-kappaB and AP-1[1].
  • SMILES
    CN1[C@]2([H])C3=C(CC1)C=C(OCO4)C4=C3C5=CC(OC)=C(OC)C=C5C2.Cl
  • UNSPSC
    12352200