Diclofenac-d4 (sodium)

MedChem Express

Diclofenac-d4 (sodium) [154523-54-3]

10

154523-54-3

Research Use Only

99.29

C14H6D4Cl2NNaO2

322.16

Diclofenac-d 4 (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 microM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

O=C(O[Na])CC(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=C(C=CC=C2Cl)Cl

2°C to 8°C

12352200