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Diclofenac free acid [15307-86-5]

Research Use Only
D3210
LKT Laboratories
Estimated Purity≥99%
Product group Chemicals
€ 493,00
10 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Diclofenac free acid [15307-86-5]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Format
    Insoluble in water. Soluble in DMSO.
  • Scientific Description
    Somewhat selective in inhibiting COX-2 over COX-1; Voltarol
  • Storage Instruction
    Ambient
  • UNSPSC
    12352200

References

  • Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338. Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586. Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723. Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1alfa and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.