Diclofenac free acid [15307-86-5]
D3210
Estimated Purity≥99%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameDiclofenac free acid [15307-86-5]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥99%
- FormatInsoluble in water. Soluble in DMSO.
- Scientific DescriptionSomewhat selective in inhibiting COX-2 over COX-1; Voltarol
- Storage InstructionAmbient
- UNSPSC12352200
References
- Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338. Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586. Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723. Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1alfa and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.