Diethyl-Lodoxamide [53882-13-6]

MedChem Express

Diethyl-Lodoxamide

9

53882-13-6

Research Use Only

C15H14ClN3O6

367.74

Diethyl-Lodoxamide is a highly potent GPR35 agonist with potential to inhibit inflammatory bowel disease. Diethyl-Lodoxamide activates GPR35 in humans, mice and rats, showing similar EC50 values. Diethyl-Lodoxamide can alleviate the clinical symptoms of DSS-induced inflammatory bowel disease in mouse models, and the effect is better than the traditional drug 5-ASA. The pharmaceutical properties of Diethyl-Lodoxamide have been optimized to better meet the requirements of drug design[1].

N#CC1=CC(NC(C(OCC)=O)=O)=C(Cl)C(NC(C(OCC)=O)=O)=C1

12352200