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Dihydroberberine (Standard)

HY-N1934R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Dihydroberberine (Standard) [483-15-8]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Dihydroberberine (Standard) is the analytical standard of Dihydroberberine. This product is intended for research and analytical applications. Dihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene (hERG) channel and significantly reduces the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-kappaB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy [1] [2] .
  • UNSPSC
    41116135