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ProductsBack/Diosgenin [512-04-9]

Diosgenin [512-04-9]

Research Use Only
D3355
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 102,00
5 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Diosgenin [512-04-9]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Soluble in CHCl3 (20mg/mL).
  • Scientific Description
    Steroidal saponin found in Dioscorea.; (25R)-5-Spirosten-3beta-ol, 3beta-Hydroxy-5-spirostene
  • Storage Instruction
    Ambient
  • UNSPSC
    12352200

References

  • He Z, Chen H, Li G, et al. Diosgenin inhibits the migration of human breast cancer MDA-MB-231 cells by suppressing Vav2 activity. Phytomedicine. 2014 Mar 18. [Epub ahead of print]. PMID: 24656238. Tohda C, Urano T, Umezaki M, et al. Diosgenin is an exogenous activator of 1,25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice. Sci Rep. 2012;2:535. PMID: 22837815. Uemura T, Goto T, Kang MS, et al. Diosgenin, the main aglycon of fenugreek, inhibits LXRalfa activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice. J Nutr. 2011 Jan;141(1):17-23. PMID: 21106928. Jung DH, Park HJ, Byun HE, et al. Diosgenin inhibits macrophage-derived inflammatory mediators through downregulation of CK2, JNK, NF-kappaB and AP-1 activation. Int Immunopharmacol. 2010 Sep;10(9):1047-54. PMID: 20601188.