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ProductsBack/Diphenhydramine Hydrochloride [147-24-0]

Diphenhydramine Hydrochloride [147-24-0]

Research Use Only
D3462
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 116,00
25 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Diphenhydramine Hydrochloride [147-24-0]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Soluble in acetone (20 mg/mL), water (1 g/mL), and alcohol (500 mg/mL). Slightly soluble in benzene or ether.
  • Scientific Description
    Voltage-gated Na+ channel blocker, mAChR antagonist, histamine H1 inverse agonist.; Alledryl, Amidryl, Benadryl, Dihydral, Dolestan, Halbmond, Noctomin, Syntedril
  • Storage Instruction
    Ambient
  • UNSPSC
    12352200

References

  • Raphael GD, Angello JT, Wu MM, et al. Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2006 Apr;96(4):606-14. PMID: 16680933. Yamashiro K, Kiryu J, Tsujikawa A, et al. Suppressive effects of histamine H1 receptor antagonist diphenhydramine on the leukocyte infiltration during endotoxin-induced uveitis. Exp Eye Res. 2001 Jul;73(1):69-80. PMID: 11428864. Kim YS, Shin YK, Lee C, et al. Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine. Brain Res. 2000 Oct 27;881(2):190-8. PMID: 11036158. Reiner PB, Kamondi A. Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current. Neuroscience. 1994 Apr;59(3):579-88. PMID: 8008209.