DL 175 [2487253-25-6]

TargetMol Chemicals

DL 175 [2487253-25-6]

999

Chemical

Research Use Only

DL 175

C17H14ClNO2

299.75

Potent and selective GPR84 biased agonist (EC50 = 33 nM). Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis.

3 years

-20°C

12352200