DL-Menthol

MedChem Express

DL-Menthol [89-78-1]

10

89-78-1

Research Use Only

98.0

C10H20O

156.27

DL-Menthol (Racementhol) is an orally active, GABAaR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABAAR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production[1][2].

C[C@H]1C[C@@H](O)[C@H](C(C)C)CC1

-20°C,2°C to 8°C

12352200