Bio-Connect

DM3-SMe

HY-130081
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DM3-SMe
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Scientific Description
    DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs) , which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC 50 of 0.0011 nM [1] [2] .
  • UNSPSC
    41116133