DMA-135 (hydrochloride)

MedChem Express

DMA-135 hydrochloride

5

Research Use Only

98.22%

C16H18ClN7O

359.81

DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies.

O=C(C1=NC(C#CC2=CC=CC=C2)=C(N(C)C)N=C1N)NC(N)=N.Cl

2°C to 8°C,-20°C,-80°C

12352200