DMAP1 antibody, PAb
ORB67071
Overview
- SupplierBiorbyt
- Product NameDMAP1 antibody, PAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:1000-1:5000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit polyclonal to DMAP1.DNA methyltransferase 1-associated protein 1 (DMAP1) is a subunit of several distinct complexesinvolved in the repression or activation of transcription. DMAP1 can independently represstranscription and is targeted to replication foci throughout S phase by interacting directly with the Nterminusof DNA methyltransferase 1 (DNMT1). During late S phase, histone deacetylase 2 (HDAC2)is added to this complex, providing a means to deacetylate histones in transcriptionally inactiveheterochromatin following replication. DMAP1 is also a component of the nucleosomeacetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibilitygene 101 and the pro-apoptotic death-associated protein 6, among others.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203