DMGDH Polyclonal Antibody

Reddot Biotech

DMGDH Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

2.1 mg/ml

Unconjugated

DMGDH

dimethylglycine dehydrogenase

dimethylglycine dehydrogenase, mitochondrial; DMGDHD; ME2GLYDH

Rabbit

IgG

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Human

-20°C

12352203