Bio-Connect
Chemical Structure
Chemical Structure
Chemical Structure

DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC)

Research Use Only
IAX-700-400
Innaxon
CAS Number18194-24-6
Product group Chemicals
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Innaxon
  • Product Name
    DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC)
  • Delivery Days Customer
    10
  • CAS Number
    18194-24-6
  • Certification
    Research Use Only
  • Scientific Description
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Its utility extends to investigating the influence of lipids on enzymatic activity and protein function when formulated into nanodiscs, LNP or liposomes. Phosphatidylcholines are zwitterionic phospholipids containing choline as part of the polar head group. At physiological pH, phosphocholine has an overall neutral charge. Furthermore, this compound has proven valuable in exploring the interplay between lipids and proteins, elucidating their interactions, and unraveling the impact of lipids on protein structure and functionality. Lipodisq™ are nanosized lipid-based discoidal particles that can be manufactured with P(SMA)/ SMALP and lipids such as DMPC (14:0 PC) (DMPC: IAX-700-400) to incorporate hydrophobic, poorly water-soluble active compounds, such as peptides, lipids, lipoproteins, transmembrane proteins and glycolipids. Applications of Lipodisq™ include functional and structural characterisation of the cargo and drug delivery with improved bioavailability, and biological half-life in vivo (PD/PK) or delivery of antigens preserved in their native comformation for immunization purposes. - Chemical. CAS: 18194-24-6. Formula: C36H72NO8P. MW: 677.9. Insoluble in water or DMSO.Soluble in ethanol, methanol or chloroform. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Its utility extends to investigating the influence of lipids on enzymatic activity and protein function when formulated into nanodiscs, LNP or liposomes. Phosphatidylcholines are zwitterionic phospholipids containing choline as part of the polar head group. At physiological pH, phosphocholine has an overall neutral charge. Furthermore, this compound has proven valuable in exploring the interplay between lipids and proteins, elucidating their interactions, and unraveling the impact of lipids on protein structure and functionality. Lipodisq™ are nanosized lipid-based discoidal particles that can be manufactured with P(SMA)/ SMALP and lipids such as DMPC (14:0 PC) (DMPC: IAX-700-400) to incorporate hydrophobic, poorly water-soluble active compounds, such as peptides, lipids, lipoproteins, transmembrane proteins and glycolipids. Applications of Lipodisq™ include functional and structural characterisation of the cargo and drug delivery with improved bioavailability, and biological half-life in vivo (PD/PK) or delivery of antigens preserved in their native comformation for immunization purposes.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200