DMX-5804

Biorbyt

DMX-5804 [2306178-56-1]

16

2306178-56-1

Research Use Only

C21H19N3O3

361.3939

DMX-5804 is a potent, orally active and selective?MAP4K4?inhibitor, with an?IC50?of 3 nM, a?pIC50?of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96).

O(C([H])([H])C([H])([H])OC([H])([H])[H])C1C([H])=C([H])C(=C([H])C=1[H])C1=C([H])N(C2C([H])=C([H])C([H])=C([H])C=2[H])C2=C1C(N([H])C([H])=N2)=O

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