DNA gyrase B-IN-2

TargetMol Chemicals

DNA gyrase B-IN-2

999

Chemical

Research Use Only

DNA gyrase B-IN-2

C18H18Cl2N4O4S

457.33

DNA gyrase B-IN-2 (Compound E), a 2-aminobenzothiazole derivative, serves as a potent inhibitor of DNA gyrase B with substantial efficacy against ESKAPE pathogens. It demonstrates nanomolar-range inhibition (IC 50 < 10 nM) and a broad-spectrum antibacterial effect, with minimum inhibitory concentrations below 0.03 microg/mL for most Gram-positive species and between 4-16 microg/mL for Gram-negative species including E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae. DNA gyrase B-IN-2 is applicable in infection research [1].

3 years

-20°C

51202000