DNA ss Antibody

LifeSpan BioSciences

DNA ss Antibody

23

Specifically reactive with single-stranded DNA and is ideal for the detection of apoptotic cells in suspension or in tissue sections. Does not recognize DNA in double-stranded conformations.

Provides a cellular marker specific for apoptotic death that is independent of internucleosomal DNA fragmentation and is useful for the detection of different stages of apoptosis in various cell types. Antibody reacts specifically with deoxycytidine and requires stretch of ssDNA of at least 25-30 bases in length for the binding. Importantly, in contrast with the TUNEL method, monoclonal antibodies to ssDNA are specific for apoptotic cell death and do not detect necrotic cells. Suitable for use in Immunoprecipitation, Immunohistochemistry (formalin fixed, paraffin embedded tissues; 4% PF frozen tissues), Flow Cytometry.. Flo, IHC, IHC-Fr, IHC-P, IP Provides a cellular marker specific for apoptotic death that is independent of internucleosomal DNA fragmentation and is useful for the detection of different stages of apoptosis in various cell types. Antibody reacts specifically with deoxycytidine and requires stretch of ssDNA of at least 25-30 bases in length for the binding. Importantly, in contrast with the TUNEL method, monoclonal antibodies to ssDNA are specific for apoptotic cell death and do not detect necrotic cells. Suitable for use in Immunoprecipitation, Immunohistochemistry (formalin fixed, paraffin embedded tissues; 4% PF frozen tissues), Flow Cytometry.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

Unconjugated

...

Mouse

IgM

12352203