DNAJB4 Polyclonal Antibody

Reddot Biotech

DNAJB4 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

DNAJB4

DnaJ heat shock protein family (Hsp40) member B4

DjB4; DnaJ (Hsp40) homolog, subfamily B, member 4; dnaJ homolog subfamily B member 4; DnaJ-like heat shock protein 40; DNAJW; heat shock 40 kDa protein 1 homolog; heat shock protein 40 homolog; HLJ1; HSP40 homolog; human liver DnaJ-like protein

Rabbit

IgG

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C

12352203