WB analysis of HEK293 overexpressing DNMT3A (A) or mock (B) cell lysate using GTX13887 DNMT3A antibody [64B814.1]. Dilution : 1 microg/ml
![WB analysis of HEK293 overexpressing mouse DNMT3A (Lanes 1) or mouse DNMT3B (Lane 2) cell lysate using GTX13887 DNMT3A antibody [64B814.1]. Dilution : 2 microg/ml](https://www.genetex.com/upload/website/prouct_img/normal/GTX13887/GTX13887_1049_WB_w_23060620_132.webp "WB analysis of HEK293 overexpressing mouse DNMT3A (Lanes 1) or mouse DNMT3B (Lane 2) cell lysate using GTX13887 DNMT3A antibody [64B814.1]. Dilution : 2 microg/ml")
![FACS (Intracellular staining) analysis of HeLa cells using GTX13887 DNMT3A antibody [64B814.1]. Blue : Primary antibody Orange : isotype control Fixation : 4% PFA](https://www.genetex.com/upload/website/prouct_img/normal/GTX13887/GTX13887_77_FACS_w_23060620_193.webp "FACS (Intracellular staining) analysis of HeLa cells using GTX13887 DNMT3A antibody [64B814.1]. Blue : Primary antibody Orange : isotype control Fixation : 4% PFA")
WB analysis of HEK293 overexpressing DNMT3A (A) or mock (B) cell lysate using GTX13887 DNMT3A antibody [64B814.1]. Dilution : 1 microg/ml
DNMT3A antibody [64B814.1]
GTX13887
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetDnmt3a
Overview
- SupplierGeneTex
- Product NameDNMT3A antibody [64B814.1] - Overexpression Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 3 microg/ml. ICC/IF: 5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID64B814.1
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID13435
- Target nameDnmt3a
- Target descriptionDNA methyltransferase 3A
- Target synonymscysteine methyltransferase DNMT3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase MmuIIIA; DNA MTase MmuIIIA; MmuIIIA
- HostMouse
- IsotypeIgG1
- Protein IDO88508
- Protein NameDNA (cytosine-5)-methyltransferase 3A
- Scientific DescriptionRequired for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203