IHC-P analysis of human breast carcinoma tissue using GTX22851 DNMT3B antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0) microwaved for 8-15 min Dilution : 1:500
IHC-P analysis of human breast carcinoma tissue using GTX22851 DNMT3B antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0) microwaved for 8-15 min Dilution : 1:500
DNMT3B antibody
GTX22851
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetDnmt3b
Overview
- SupplierGeneTex
- Product NameDNMT3B antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody has been used to detect both recombinant and endogenous DNMT3b and recombinant DNMT3a.
- Application Supplier NoteWB: 2.0 microg/ml. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID13436
- Target nameDnmt3b
- Target descriptionDNA methyltransferase 3B
- Target synonymsDNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase MmuIIIB; DNA MTase MmuIIIB; MmuIIIB
- HostRabbit
- IsotypeIgG
- Protein IDO88509
- Protein NameDNA (cytosine-5)-methyltransferase 3B
- Scientific DescriptionThis is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Nov 2012]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Protein phosphatase 2A inactivation induces microsatellite instability, neoantigen production and immune response. Yen YT et al., 2021 Dec 15, Nat CommunRead more