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Docetaxel-d5 (trihydrate)

HY-B0011AS
MedChem Express
Molecular Weight866.96
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Docetaxel-d5 (trihydrate)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C43H54D5NO17
  • Molecular Weight
    866.96
  • Scientific Description
    Docetaxel-d 5 (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 microM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].
  • SMILES
    O=C(OC(C)(C)C)N[C@H]([C@H](C(O[C@@H]1C(C)=C([C@@H](O)C([C@@]2(C)[C@]([C@@](CO3)(OC(C)=O)[C@@]3([H])C[C@@H]2O)([H])[C@@H]4OC(C5=C([2H])C([2H])=C([2H])C([2H])=C5[2H])=O)=O)C(C)(C)[C@@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O
  • UNSPSC
    12352200