DOCK2 Polyclonal Antibody
RD267583A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetDOCK2
Overview
- SupplierReddot Biotech
- Product NameDOCK2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1794
- Target nameDOCK2
- Target descriptiondedicator of cytokinesis 2
- Target synonymsdedicator of cyto-kinesis 2; dedicator of cytokinesis protein 2; IMD40
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203