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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DOK4 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DOK4 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DOK4 Polyclonal Antibody at dilution 1:50

DOK4 Polyclonal Antibody

Research Use Only
E-AB-10910
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    DOK4 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.5mg/ml
  • Scientific Description
    Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
  • UNSPSC
    12352203