Doramapimod (BIRB-796)
ORB251412
CAS Number285983-48-4
Product group Chemicals
Molecular Weight527.66
Overview
- SupplierBiorbyt
- Product NameDoramapimod (BIRB-796) [285983-48-4]
- Delivery Days Customer16
- CAS Number285983-48-4
- CertificationResearch Use Only
- Molecular FormulaC31H37N5O3
- Molecular Weight527.66
- Scientific DescriptionBIRB 796 (Doramapimod) is a highly selective p38alpha MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCalpha/beta/gamma.
- SMILESO=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3
- UNSPSC12352200