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Doramapimod (hydrochloride)

HY-10320A
MedChem Express
Molecular Weight564.12
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Doramapimod (hydrochloride)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C31H38ClN5O3
  • Molecular Weight
    564.12
  • Scientific Description
    Doramapimod hydrochloride (BIRB 796 hydrochloride) is an anti-inflammatory compound with biological activity through inhibition of p38 MAPK. Doramapimod hydrochloride can significantly inhibit the activities of TNF-alpha and IL-1beta induced by LPS, LTA and PGN. Doramapimod hydrochloride showed a stronger inhibitory effect on inflammation induced by all three bacterial toxins, which was more significant compared with the effects of other compounds. Doramapimod hydrochloride can be used in the research of autoimmune diseases [1] .
  • SMILES
    O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3.Cl
  • UNSPSC
    12352200