Dorsomorphin Dihydrochloride [1219168-18-9]
D582705
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameDorsomorphin Dihydrochloride [1219168-18-9]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatWater (100 mM), DMSO (20 mM).
- Scientific DescriptionInhibitor of ALK2, ALK3, ALK6, and AMPK.; Dorsomorphin 2HCl; BML-275; BML-275 2HCl; Compound C; AK175513; 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;dihydrochloride
- Storage Instruction4°C
- UNSPSC12352200
References
- Yu P., Hong C., et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 34(1):33-41 (2008). PMID: 18026094. Vucicevic L., Misirkic M., et al. Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. Autophagy. 7(1):40-50 (2011). PMID: 20980833. Horbelt D., Boergermann J., et al. Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation. J Biol Chem. 290(6):3390-404 (2015). PMID: 25368322.