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ProductsBack/Dorsomorphin Dihydrochloride [1219168-18-9]

Dorsomorphin Dihydrochloride [1219168-18-9]

Research Use Only
D582705
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 132,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Dorsomorphin Dihydrochloride [1219168-18-9]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Water (100 mM), DMSO (20 mM).
  • Scientific Description
    Inhibitor of ALK2, ALK3, ALK6, and AMPK.; Dorsomorphin 2HCl; BML-275; BML-275 2HCl; Compound C; AK175513; 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;dihydrochloride
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Yu P., Hong C., et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 34(1):33-41 (2008). PMID: 18026094. Vucicevic L., Misirkic M., et al. Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. Autophagy. 7(1):40-50 (2011). PMID: 20980833. Horbelt D., Boergermann J., et al. Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation. J Biol Chem. 290(6):3390-404 (2015). PMID: 25368322.