Doxorubicin Hydrochloride [25316-40-9]
D5794
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameDoxorubicin Hydrochloride [25316-40-9]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSoluble in water, methanol or aqueous alcohols. Soluble in DMSO to 10 mg/mL. Insoluble in acetone or chloroform.
- Scientific DescriptionAnthracycline, DNA intercalator; topoisomerase II inhibitor.; Adriacin, Adriblastina, Adriamycin, Caelyx
- Storage Instruction4°C
- UNSPSC12352200
References
- Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267. Tacar O, Sriamornsak P, Dass CR. Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J Pharm Pharmacol. 2013 Feb;65(2):157-70. PMID: 23278683. Gamo FJ, Sanz LM, Vidal J, et al. Thousands of chemical starting points for antimalarial lead identification. Nature. 2010 May 20;465(7296):305-10. PMID: 20485427. Squillace RM, Miller D, Cookson M, et al. Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models. Mol Cancer Ther. 2011 Oct;10(10):1959-1968. PMID: 21825008.