DROSHA Antibody, Biotin conjugated
CSB-PA889096LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetDROSHA
Overview
- SupplierCusabio
- Product NameDROSHA Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- Gene ID29102
- Target nameDROSHA
- Target descriptiondrosha ribonuclease III
- Target synonymsdrosha, double-stranded RNA-specific endoribonuclease; ETOHI2; HSA242976; nuclear RNase III Drosha; p241; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; RANSE3L; ribonuclease 3; ribonuclease type III, nuclear; RN3; RNase III; RNASE3L; RNASEN
- HostRabbit
- IsotypeIgG
- Protein IDQ9NRR4
- Protein NameRibonuclease 3
- Scientific DescriptionRibonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3 and 5 strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203