Bio-Connect

DROSHA Antibody, Biotin conjugated

CSB-PA889096LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetDROSHA
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Cusabio
  • Product Name
    DROSHA Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID29102
  • Target name
    DROSHA
  • Target description
    drosha ribonuclease III
  • Target synonyms
    drosha, double-stranded RNA-specific endoribonuclease; ETOHI2; HSA242976; nuclear RNase III Drosha; p241; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; RANSE3L; ribonuclease 3; ribonuclease type III, nuclear; RN3; RNase III; RNASE3L; RNASEN
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NRR4
  • Protein Name
    Ribonuclease 3
  • Scientific Description
    Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3 and 5 strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203