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DS45500853

DS45500853

Research Use Only
T40349
TargetMol Chemicals
CAS Number2735803-28-6
Product group Chemicals
Molecular Weight284.355
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    DS45500853
  • Delivery Days Customer
    14
  • CAS Number
    2735803-28-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    DS45500853
  • Molecular Formula
    C18H20O3
  • Molecular Weight
    284.355
  • Scientific Description
    DS45500853, an estrogen-related receptor alfa (ERRalfa) agonist, acts as an inhibitor of the binding interaction between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRalfa ligand-binding domain (LBD; 1.2 uM), exhibiting an IC50 of 0.80 uM. This compound holds potential for research pertaining to metabolic disorders, particularly type 2 diabetes mellitus (T2DM).
  • Shelf life instruction
    3 years
  • SMILES
    CC(=O)c1ccc(Oc2ccc(O)c(c2)C(C)(C)C)cc1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Shinozuka T, et al. Discovery of a Novel Class of ERRα Agonists. ACS Med Chem Lett. 2021 Apr 21;12(5):817-821.
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