Duocarmycin SA [130288-24-3]
T11118
CAS Number130288-24-3
Product group Chemicals
Molecular Weight477.47
Overview
- SupplierTargetMol Chemicals
- Product NameDuocarmycin SA
- Delivery Days Customer9
- CAS Number130288-24-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameDuocarmycin SA
- Molecular FormulaC25H23N3O7
- Molecular Weight477.47
- Scientific DescriptionDuocarmycin SA is an extremely potent cytotoxic agent and antitumor antibiotic that induces sequence-selective alkylation of duplex DNA, with an IC50 of 10 pM. It demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells when combined with proton radiation in vitro.
- Shelf life instruction3 years
- SMILESC(=O)(N1C=2[C@]3([C@](C3)(C1)[H])C4=C(NC(C(OC)=O)=C4)C(=O)C2)C=5NC=6C(C5)=CC(OC)=C(OC)C6OC
- Storage Instruction-20°C
- UNSPSC12352200