
IHC-P analysis of human prostate using GTX47608 DUSP1 antibody, C-term. Antigen retrieval : citrate buffer pH 6 Dilution : 3.8microg/ml
DUSP1 antibody, C-term
GTX47608
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetDUSP1
Overview
- SupplierGeneTex
- Product NameDUSP1 antibody, C-term
- Delivery Days Customer7
- Application Supplier NoteWB: 0.3-1microg/ml. IHC-P: 3-5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID1843
- Target nameDUSP1
- Target descriptiondual specificity phosphatase 1
- Target synonymsCL 100; CL100; dual specificity protein phosphatase 1; dual specificity protein phosphatase hVH1; HVH1; MAP kinase phosphatase 1; mitogen-activated protein kinase phosphatase 1; MKP1; MKP-1; protein-tyrosine phosphatase CL100; PTPN10; serine/threonine specific protein phosphatase
- HostGoat
- IsotypeIgG
- Protein IDP28562
- Protein NameDual specificity protein phosphatase 1
- Scientific DescriptionThe protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- DUSP1 promotes muscle atrophy by inhibiting myocyte differentiation in cachectic patients.Read more