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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using DUSP8 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using DUSP8 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using DUSP8 Polyclonal Antibody at dilution 1:40

DUSP8 Polyclonal Antibody

E-AB-12399
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    DUSP8 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.4mg/ml
  • Scientific Description
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.
  • UNSPSC
    12352203