DUSP8 Polyclonal Antibody
![Research Use Only](static/images/certificates/ruo.jpg)
RD78490A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetDUSP8
Overview
- SupplierReddot Biotech
- Product NameDUSP8 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID1850
- Target nameDUSP8
- Target descriptiondual specificity phosphatase 8
- Target synonymsC11orf81; dual specificity protein phosphatase 8; dual specificity protein phosphatase hVH-5; H1 phosphatase, vaccinia virus homolog; HB5; HVH-5; HVH8; serine/threonine specific protein phosphatase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203