DY268

MedChem Express

DY268 [1609564-75-1]

10

1609564-75-1

Research Use Only

99.32

C30H32N4O5S

560.66

DY268 is a farnesoid X receptor (FXR) antagonist ( IC 50 =7.5 nM). It inhibits FXR transactivation in a cell-based assay with an IC 50 value of 468 nM. DY268 can be used in the study of drug-induced liver injury (DILI) [1] [2] .

O=C(C1=CN(CC2=CC(OC)=CC=C2)N=C1C3=CC=C(C)C=C3)NC4=CC=C(C)C(S(=O)(N5CCOCC5)=O)=C4

-20°C,2°C to 8°C

12352200