Dyrk1A/B-IN-1

MedChem Express

Dyrk1A/B-IN-1 [3032401-50-3]

10

Research Use Only

C21H17N3O2S2

407.51

Dyrk1A/B-IN-1 (compound 3n) is a potent, selective and cell-permeable DYRK1A and DYRK1B inhibitor with Kis of 67.8 nM and 237.9 nM, and IC50s of 1.1 microM and 0.8 microM, respectively. Dyrk1A/B-IN-1 is not toxic to human cells. Dyrk1A/B-IN-1 can be used for researching DYRK1A and DYRK1B cellular functions and their role in pathologies[1].

NC(C1=CC2=C(C=CC=C2S1)C3=CC=C(S3)C(NCC4=C(C=CC=C4)N)=O)=O

12131703