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ProductsBack/E 2012 [870843-42-8]
E 2012 [870843-42-8]

E 2012 [870843-42-8]

Research Use Only
T15184
TargetMol Chemicals
CAS Number870843-42-8
Product group Chemicals
Estimated Purity99.83%
Molecular Weight419.49
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    E 2012
  • Delivery Days Customer
    4
  • CAS Number
    870843-42-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    E 2012
  • Estimated Purity
    99.83%
  • Molecular Formula
    C25H26FN3O2
  • Molecular Weight
    419.49
  • Scientific Description
    E2012 is a gamma-secretase modulator (GSM). E2012 inhibits 3beta-hydroxysterol delta24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimers disease by reduction of amyloid beta-42, and induces cataract following repeated doses in the rat.
  • Shelf life instruction
    3 years
  • SMILES
    COc1cc(\C=C2/CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200