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(E)-4-Hydroxycrotonic acid

HY-100982
MedChem Express
CAS Number24587-49-3
Product group Chemicals
Estimated Purity95.0
Molecular Weight102.09
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (E)-4-Hydroxycrotonic acid [24587-49-3]
  • Delivery Days Customer
    9
  • CAS Number
    24587-49-3
  • Estimated Purity
    95.0
  • Molecular Formula
    C4H6O3
  • Molecular Weight
    102.09
  • Scientific Description
    (E)-4-Hydroxycrotonic acid (T-HCA) is a high-affinity ligand for GHB binding sites, with a k i value of 1.1 microM. The introduction of diaryl substituents into (E)-4-Hydroxycrotonic acid significantly enhances its affinity for GHB binding sites, with k i values ranging from 0.023 to 0.075 microM. (E)-4-Hydroxycrotonic acid holds promise for optimizing GHB ligand structures and assisting in the development of effective three-dimensional pharmacophore models [1] .
  • SMILES
    O=C(O)/C=C/CO
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200