E-4177 [135070-05-2]

TargetMol Chemicals

E-4177 [135070-05-2]

72

Chemical

Research Use Only

E-4177

C24H21N3O2

383.44

E-4177 is an angiotensin type 1 receptor antagonist. In rat adrenal cortex and liver, E4177 competitively inhibited the specific binding of 125I-[Sar1,Ile8]Ang II, with IC50 being (5.2 +/- 1.0) x 10(-8) M for the adrenal cortex and (1.2 +/- 0.3) x 10(-7) M for the liver.

3 years

C(N1C(=NC=2C1=NC=CC2C)C3CC3)C4=CC=C(C=C4)C5=C(C(O)=O)C=CC=C5

-20°C

12352200